Ontology highlight
ABSTRACT:
SUBMITTER: Curtis D
PROVIDER: S-EPMC3024533 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Curtis David D Vine Anna E AE McQuillin Andrew A Bass Nicholas James NJ Pereira Ana A Kandaswamy Radhika R Lawrence Jacob J Anjorin Adebayo A Choudhury Khalid K Datta Susmita R SR Puri Vinay V Krasucki Robert R Pimm Jonathan J Thirumalai Srinivasa S Quested Digby D Gurling Hugh M D HM
Psychiatric genetics 20110201 1
<h4>Objective</h4>There are theoretical reasons why comparing marker allele frequencies between cases of different diseases, rather than with controls, may offer benefits. The samples may be better matched, especially for background risk factors common to both diseases. Genetic loci may also be detected which influence which of the two diseases occurs if common risk factors are present.<h4>Method</h4>We used samples of UK bipolar and schizophrenic cases that had earlier been subject to genome-wi ...[more]