Clinical trials and progress with paclitaxel in ovarian cancer.
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ABSTRACT:
SUBMITTER: Kumar S
PROVIDER: S-EPMC3024893 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
Publications
Clinical trials and progress with paclitaxel in ovarian cancer.
Kumar Sanjeev S Mahdi Haider H Bryant Christopher C Shah Jay P JP Garg Gunjal G Munkarah Adnan A
International journal of women's health 20101119
Paclitaxel is a front-line agent for ovarian cancer chemotherapy, along with the platinum agents. Derived from the Pacific yew tree, Taxus brevifolia, paclitaxel has covered significant ground from the initial discovery of its antineoplastic properties to clinical applications in many forms of human cancers, including ovarian cancer. Although much has been published about the unique mechanism of action of this agent, several issues remain to be resolved. Finding the appropriate dosage schedule f ...[more]
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