Ontology highlight
ABSTRACT:
SUBMITTER: Massich MD
PROVIDER: S-EPMC3025450 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
ACS nano 20101001 10
Nanoparticles are finding utility in myriad biotechnological applications, including gene regulation, intracellular imaging, and medical diagnostics. Thus, evaluating the biocompatibility of these nanomaterials is imperative. Here we use genome-wide expression profiling to study the biological response of HeLa cells to gold nanoparticles functionalized with nucleic acids. Our study finds that the biological response to gold nanoparticles stabilized by weakly bound surface ligands is significant ...[more]