Ontology highlight
ABSTRACT:
SUBMITTER: Krumbiegel M
PROVIDER: S-EPMC3025781 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Krumbiegel Mandy M Pasutto Francesca F Schlötzer-Schrehardt Ursula U Uebe Steffen S Zenkel Matthias M Mardin Christian Y CY Weisschuh Nicole N Paoli Daniela D Gramer Eugen E Becker Christian C Ekici Arif B AB Weber Bernhard H F BH Nürnberg Peter P Kruse Friedrich E FE Reis André A
European journal of human genetics : EJHG 20100901 2
Genetic and nongenetic factors contribute to development of pseudoexfoliation (PEX) syndrome, a complex, age-related, generalized matrix process frequently associated with glaucoma. To identify specific genetic variants underlying its etiology, we performed a genome-wide association study (GWAS) using a DNA-pooling approach. Therefore, equimolar amounts of DNA samples of 80 subjects with PEX syndrome, 80 with PEX glaucoma (PEXG) and 80 controls were combined into separate pools and hybridized to ...[more]