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Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody.


ABSTRACT: Geometrically enhanced differential immunocapture (GEDI) and an antibody for prostate-specific membrane antigen (PSMA) are used for high-efficiency and high-purity capture of prostate circulating tumor cells from peripheral whole blood samples of castrate-resistant prostate cancer patients.

SUBMITTER: Gleghorn JP 

PROVIDER: S-EPMC3031459 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature

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Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody.

Gleghorn Jason P JP   Pratt Erica D ED   Denning Denise D   Liu He H   Bander Neil H NH   Tagawa Scott T ST   Nanus David M DM   Giannakakou Paraskevi A PA   Kirby Brian J BJ  

Lab on a chip 20091116 1


Geometrically enhanced differential immunocapture (GEDI) and an antibody for prostate-specific membrane antigen (PSMA) are used for high-efficiency and high-purity capture of prostate circulating tumor cells from peripheral whole blood samples of castrate-resistant prostate cancer patients. ...[more]

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