Dataset Information

Mobilization of soil-bound residue of organochlorine pesticides and polycyclic aromatic hydrocarbons in an in vitro gastrointestinal model.

ABSTRACT: A previous study on mobilization of organochlorine pesticides (OCPs) in contaminated soils from the field revealed that the total amount of OCPs measured in digestive fluid and chyme of an in vitro gastrointestinal model was higher than the quantity directly extracted using a solvent extraction without digestion, providing a clue that the bound residue of OCPs might be mobilized. This hypothesis was tested in this study for both OCPs and polycyclic aromatic hydrocarbons (PAHs). Three contaminated surface soil samples with different organic carbon (OC) contents were collected from the field, and extracted with a solvent with and without digestion in an in vitro gastrointestinal model. It was found that bound residues of OCPs and PAHs were mobilized to a certain extent during digestion. The ratios of the mobilized bound residues over the total quantities extracted after digestion (R(b)) varied from 0 to 0.96 for individual compounds. The R(b) was positively correlated with OC content. Among the five constitutes of digestive juice, bile salt was the only one that served to mobilize the bound residues and the extractability of bile salt was constant over a concentration range from 2 to 20 mg/mL. The mobilization process followed typical first-order kinetics. The calculated rate constants suggest that mobilization was fast and 90% of extracted bound residues of OCPs and PAHs were mobilized within 2.4 and 4.8 h, respectively.

SUBMITTER: Tao S

PROVIDER: S-EPMC3031735 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature

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Mobilization of soil-bound residue of organochlorine pesticides and polycyclic aromatic hydrocarbons in an in vitro gastrointestinal model.

Tao Shu S Li Li L Ding Junnan J Zhong Junjun J Zhang Diyu D Lu Yan Y Yang Yifeng Y Wang Xilong X Li Xiqing X Cao Jun J Lu Xiaoxia X Liu Wenxin W

Environmental science & technology 20101222 3

A previous study on mobilization of organochlorine pesticides (OCPs) in contaminated soils from the field revealed that the total amount of OCPs measured in digestive fluid and chyme of an in vitro gastrointestinal model was higher than the quantity directly extracted using a solvent extraction without digestion, providing a clue that the bound residue of OCPs might be mobilized. This hypothesis was tested in this study for both OCPs and polycyclic aromatic hydrocarbons (PAHs). Three contaminate ...[more]

PMID: 21175124

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Project description:Persistent organic pollutants (POPs) have been banned over the last decades for being damaged to the environment and to the health of humans and animals. However, due to their lipophilic nature and resistance to degradation, they are frequently detected in biological samples. Its presence has been associated with the increased risk of suffering from different diseases in human series, being newborns and children especially sensitive. The present data reports umbilical cord blood levels of twenty organochlorine pesticides (aldrin, dieldrin, endrin, o,p'-DDD, p,p'-DDD, o,p'-DDE, p,p'-DDE, o,p'-DDT, p,p'-DDT, endosulfan alfa, endosulfan beta, endosulfan sulphate, heptachlor, HCB, αHCH, βHCH, δHCH, lindane, methoxychlor and mirex), eighteen polychlorinated biphenyls (congeners 28, 52, 77, 81, 101, 105, 114, 118, 123, 126, 138, 153, 156, 157, 167, 169, 180 and 189), eight bromodiphenyl ethers (congeners 28, 47, 85, 99, 100, 153, 154 and 183), and sixteen polycyclic aromatic hydrocarbons (acenaphthalene, acenaphthene, anthracene, benzo(a)anthracene, benzo(a)pyrene, benzo(b)fluoranthene, benzo(g,h,i)perylene, benzo(k)fluoranthene, chrysene, dibenzo(a,h)anthracene, fluoranthene, fluorine, indene(1,2,3-cd)pyrene, naphthalene, phenanthrene and pyrene). A total of 447 samples, representing 86.6% of the total births during the recruited period (March 1, 2015, to April 30, 2016), were available for POP analyses. POPs were determined in a Gas Chromatography (GC) system equipped with an automated sampler (Models 7890B and 7693; Agilent Technologies, Palo Alto, CA, USA) for gas chromatographic separations. The detection of the analytes was performed using a Triple Quad 7010 mass spectrometer (Agilent Technologies). All of the measurements were performed as triplicate measurements, and the means were used for the calculations. Data are reported in ng/mL. The present data also includes birth parameters, including weight, length, cranial perimeter, Apgar score and congenital malformations, and data referred to mothers (harmful habits, chronic diseases, and anthropometric/demographic characteristics).

Dataset Information

Mobilization of soil-bound residue of organochlorine pesticides and polycyclic aromatic hydrocarbons in an in vitro gastrointestinal model.

Publications

Mobilization of soil-bound residue of organochlorine pesticides and polycyclic aromatic hydrocarbons in an in vitro gastrointestinal model.

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