Ontology highlight
ABSTRACT:
SUBMITTER: Rossetti CA
PROVIDER: S-EPMC3032834 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
Rossetti C A CA Galindo C L CL Everts R E RE Lewin H A HA Garner H R HR Adams L G LG
Research in veterinary science 20101006 1
Brucellosis is a worldwide zoonotic infectious disease that has a significant economic impact on animal production and human public health. We characterized the gene expression profile of B. abortus-infected monocyte-derived macrophages (MDMs) from naïve cattle naturally resistant (R) or susceptible (S) to brucellosis using a cDNA microarray technology. Our data indicate that (1) B. abortus induced a slightly increased genome activation in R MDMs and a down-regulated transcriptome in S MDMs, dur ...[more]