Ontology highlight
ABSTRACT:
SUBMITTER: Kaito C
PROVIDER: S-EPMC3033363 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Kaito Chikara C Saito Yuki Y Nagano Gentaro G Ikuo Mariko M Omae Yosuke Y Hanada Yuichi Y Han Xiao X Kuwahara-Arai Kyoko K Hishinuma Tomomi T Baba Tadashi T Ito Teruyo T Hiramatsu Keiichi K Sekimizu Kazuhisa K
PLoS pathogens 20110203 2
The F region downstream of the mecI gene in the SCCmec element in hospital-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) contains two bidirectionally overlapping open reading frames (ORFs), the fudoh ORF and the psm-mec ORF. The psm-mec ORF encodes a cytolysin, phenol-soluble modulin (PSM)-mec. Transformation of the F region into the Newman strain, which is a methicillin-sensitive S. aureus (MSSA) strain, or into the MW2 (USA400) and FRP3757 (USA300) strains, which are communi ...[more]