Null mutation of HvrA compensates for loss of an essential relA/spoT-like gene in Rhodobacter capsulatus.
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ABSTRACT:
SUBMITTER: Masuda S
PROVIDER: S-EPMC303453 | biostudies-literature | 2004 Jan
REPOSITORIES: biostudies-literature
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Null mutation of HvrA compensates for loss of an essential relA/spoT-like gene in Rhodobacter capsulatus.
Masuda Shinji S Bauer Carl E CE
Journal of bacteriology 20040101 1
We report that a single relA/spoT-like gene exists on the Rhodobacter capsulatus chromosome, and its mutational loss is lethal. This gene could be mutated only under a mutational background of a null mutation in the nucleoid protein HvrA. This result suggests that there may be a direct link between HvrA-regulated promoters and the ppGpp-related stringent response. ...[more]
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