Ontology highlight
ABSTRACT:
SUBMITTER: Chuang JC
PROVIDER: S-EPMC3035497 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Chuang Jen-Chieh JC Cui Huxing H Mason Brittany L BL Mahgoub Melissa M Bookout Angie L AL Yu Hana G HG Perello Mario M Elmquist Joel K JK Repa Joyce J JJ Zigman Jeffrey M JM Lutter Michael M
Journal of lipid research 20100202 6
Several psychiatric disorders increase the risk of cardiovascular disease, including posttraumatic stress disorder and major depression. While the precise mechanism for this association has not yet been established, it has been shown that certain disorders promote an unfavorable lipid profile. To study the interaction of stress and lipid dysregulation, we utilized chronic social defeat stress (CSDS), a mouse model of chronic stress with features of posttraumatic stress disorder and major depress ...[more]