Ontology highlight
ABSTRACT:
SUBMITTER: Browning BL
PROVIDER: S-EPMC3035716 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Browning Brian L BL Browning Sharon R SR
American journal of human genetics 20110201 2
We present a method, fastIBD, for finding tracts of identity by descent (IBD) between pairs of individuals. FastIBD can be applied to thousands of samples across genome-wide SNP data and is significantly more powerful for finding short tracts of IBD than existing methods for finding IBD tracts in such data. We show that fastIBD can detect facets of population structure that are not revealed by other methods. In the Wellcome Trust Case Control Consortium bipolar disorder case-control data, we fin ...[more]