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MHC class I loci of the Bar-Headed goose (Anser indicus).

ABSTRACT: MHC class I proteins mediate functions in anti-pathogen defense. MHC diversity has already been investigated by many studies in model avian species, but here we chose the bar-headed goose, a worldwide migrant bird, as a non-model avian species. Sequences from exons encoding the peptide-binding region (PBR) of MHC class I molecules were isolated from liver genomic DNA, to investigate variation in these genes. These are the first MHC class I partial sequences of the bar-headed goose to be reported. A preliminary analysis suggests the presence of at least four MHC class I genes, which share great similarity with those of the goose and duck. A phylogenetic analysis of bar-headed goose, goose and duck MHC class I sequences using the NJ method supports the idea that they all cluster within the anseriforms clade.

SUBMITTER: Liang Q

PROVIDER: S-EPMC3036124 | biostudies-literature | 2010 Jul

REPOSITORIES: biostudies-literature

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MHC class I loci of the Bar-Headed goose (Anser indicus).

Liang Qinglong Q Wei Lei L Wang Xinwei X He Hongxuan H

Genetics and molecular biology 20100701 3

MHC class I proteins mediate functions in anti-pathogen defense. MHC diversity has already been investigated by many studies in model avian species, but here we chose the bar-headed goose, a worldwide migrant bird, as a non-model avian species. Sequences from exons encoding the peptide-binding region (PBR) of MHC class I molecules were isolated from liver genomic DNA, to investigate variation in these genes. These are the first MHC class I partial sequences of the bar-headed goose to be reported ...[more]

PMID: 21637434

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