Ontology highlight
ABSTRACT:
SUBMITTER: Zhong C
PROVIDER: S-EPMC3036926 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Zhong Chen C Quanzhong Yin Y Genshan Ma M Hua Zhang Z Ruolong Zheng Z Jiahong Wang W Chunheng Gao G
Genetics and molecular biology 20090401 2
We investigated the association between myeloperoxidase gene -463G > A polymorphism and premature coronary artery disease (CAD) in two Chinese population samples: 229 patients and 230 controls. Genotypes were determined by ligase detection reaction-polymerase chain reaction sequencing and the grouping technique. We found lower frequencies of both the A/A genotype and the A allele in patients (p < 0.05). Multivariate logistic regression showed that the risk of premature CAD in subjects carrying t ...[more]