A putative gene cluster from a Lyngbya wollei bloom that encodes paralytic shellfish toxin biosynthesis.
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ABSTRACT:
SUBMITTER: Mihali TK
PROVIDER: S-EPMC3037375 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Publications
A putative gene cluster from a Lyngbya wollei bloom that encodes paralytic shellfish toxin biosynthesis.
Mihali Troco K TK Carmichael Wayne W WW Neilan Brett A BA
PloS one 20110210 2
Saxitoxin and its analogs cause the paralytic shellfish-poisoning syndrome, adversely affecting human health and coastal shellfish industries worldwide. Here we report the isolation, sequencing, annotation, and predicted pathway of the saxitoxin biosynthetic gene cluster in the cyanobacterium Lyngbya wollei. The gene cluster spans 36 kb and encodes enzymes for the biosynthesis and export of the toxins. The Lyngbya wollei saxitoxin gene cluster differs from previously identified saxitoxin cluster ...[more]
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