Ontology highlight
ABSTRACT:
SUBMITTER: Zhang T
PROVIDER: S-EPMC3037562 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
Zhang Tao T Moss Arthur A Cong Peikuan P Pan Min M Chang Bingxi B Zheng Liangrong L Fang Quan Q Zareba Wojciech W Robinson Jennifer J Lin Changsong C Li Zhongxiang Z Wei Junfang J Zeng Qiang Q Qi Ming M
Human mutation 20101101 11
The Long QT Syndrome (LQTS) is a group of genetically heterogeneous disorders that predisposes young individuals to ventricular arrhythmias and sudden death. LQTS is mainly caused by mutations in genes encoding subunits of cardiac ion channels (KCNQ1, KCNH2,SCN5A, KCNE1, and KCNE2). Many other genes involved in LQTS have been described recently(KCNJ2, AKAP9, ANK2, CACNA1C, SCNA4B, SNTA1, and CAV3). We created an online database(http://www.genomed.org/LOVD/introduction.html) that provides informa ...[more]