Unknown

Dataset Information

0

New flagellin gene for Salmonella enterica serovar Typhi from the East Indonesian archipelago.


ABSTRACT: Phase variation is a property unique of some Salmonella enterica serovar Typhi strains from Indonesia. Salmonella Typhi isolates from Indonesia have been described that in addition to the phase 1 Hd flagellin gene contain a second flagellin gene named z66. S. Typhi isolates from Indonesia with a mutant Hd gene named Hj have also been described. Here, we have identified another flagellin gene of S. Typhi, named Ind, showing a closest homology with the flagellin gene of Serratia marcescens. The Ind gene was detected in 21.8% of the S. Typhi isolates from the East Indonesian archipelago, all of which contained the Hd gene. The Hj gene was not detected. The z66 gene was present in 15.4% of the isolates. The presence of these "foreign" flagellin genes could be associated with an increased risk for developing severe disease.

SUBMITTER: Hatta M 

PROVIDER: S-EPMC3042820 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature

altmetric image

Publications

New flagellin gene for Salmonella enterica serovar Typhi from the East Indonesian archipelago.

Hatta Mochammad M   Sultan Andi R AR   Pastoor Rob R   Smits Henk L HL  

The American journal of tropical medicine and hygiene 20110301 3


Phase variation is a property unique of some Salmonella enterica serovar Typhi strains from Indonesia. Salmonella Typhi isolates from Indonesia have been described that in addition to the phase 1 Hd flagellin gene contain a second flagellin gene named z66. S. Typhi isolates from Indonesia with a mutant Hd gene named Hj have also been described. Here, we have identified another flagellin gene of S. Typhi, named Ind, showing a closest homology with the flagellin gene of Serratia marcescens. The In  ...[more]

Similar Datasets

2017-10-31 | GSE93686 | GEO
| S-EPMC5664820 | biostudies-literature
| S-EPMC128351 | biostudies-literature
| S-EPMC3360705 | biostudies-literature
| S-EPMC4291426 | biostudies-literature
| S-EPMC400630 | biostudies-literature
2018-06-15 | GSE113333 | GEO
| S-EPMC525459 | biostudies-literature
| S-EPMC7083327 | biostudies-literature
| S-EPMC1070368 | biostudies-literature