Ontology highlight
ABSTRACT:
SUBMITTER: Lagging M
PROVIDER: S-EPMC3044738 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Lagging Martin M Askarieh Galia G Negro Francesco F Bibert Stephanie S Söderholm Jonas J Westin Johan J Lindh Magnus M Romero Ana A Missale Gabriele G Ferrari Carlo C Ferrari Carlo C Neumann Avidan U AU Pawlotsky Jean-Michel JM Haagmans Bart L BL Zeuzem Stefan S Bochud Pierre-Yves PY Hellstrand Kristoffer K
PloS one 20110224 2
<h4>Background</h4>High baseline levels of IP-10 predict a slower first phase decline in HCV RNA and a poor outcome following interferon/ribavirin therapy in patients with chronic hepatitis C. Several recent studies report that single nucleotide polymorphisms (SNPs) adjacent to IL28B predict spontaneous resolution of HCV infection and outcome of treatment among HCV genotype 1 infected patients.<h4>Methods and findings</h4>In the present study, we correlated the occurrence of variants at three su ...[more]