Ontology highlight
ABSTRACT:
SUBMITTER: Wei P
PROVIDER: S-EPMC3046412 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
Journal of the Royal Statistical Society. Series C, Applied statistics 20100101 1
As biological knowledge accumulates rapidly, gene networks encoding genome-wide gene-gene interactions have been constructed. As an improvement over the standard mixture model that tests all the genes iid a priori, Wei and Li (2007) and Wei and Pan (2008) proposed modeling a gene network as a Discrete- or Gaussian-Markov random field (DMRF or GMRF) respectively in a mixture model to analyze genomic data. However, how these methods compare in practical applications in not well understood and this ...[more]