Ontology highlight
ABSTRACT:
SUBMITTER: Angheloiu GO
PROVIDER: S-EPMC3049853 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Angheloiu George O GO Haka Abigail S AS Georgakoudi Irene I Arendt Joseph J Müller Markus G MG Scepanovic Obrad R OR Evanko Stephen P SP Wight Thomas N TN Mukherjee Prasun P Waldeck David H DH Dasari Ramachandra R RR Fitzmaurice Maryann M Kramer John R JR Feld Michael S MS
Atherosclerosis 20101127 1
<h4>Objectives</h4>The protein components of low-density lipoprotein (LDL), oxidized LDL and proteoglycans such as versican contain tryptophan, an amino acid with characteristic fluorescence features at 308 nm excitation wavelength. We hypothesize that intrinsic fluorescence spectroscopy at 308 nm excitation wavelength IFS308, a method suitable for clinical use, can identify coronary artery lesions with superficial foam cells (SFCs) and/or proteoglycans.<h4>Methods</h4>We subjected 119 human cor ...[more]