Ontology highlight
ABSTRACT:
SUBMITTER: Cipriani S
PROVIDER: S-EPMC3049925 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Cipriani Sara S Chen Xiqun X Schwarzschild Michael A MA
Biomarkers in medicine 20101001 5
A growing number of studies have correlated higher urate levels with a lower risk of developing Parkinson's disease (PD) and with a favorable rate of disease progression, indicating that urate could be an important biomarker of the pathophysiology underlying PD. Dietary and genetic determinants of urate have also been linked to a reduced risk or delayed onset of PD. Based on the known antioxidant and metal complexing properties of urate, together with evidence for oxidative stress as a contribut ...[more]