5-oxo-15-HETE: total synthesis and bioactivity.
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ABSTRACT:
SUBMITTER: Patel P
PROVIDER: S-EPMC3052199 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Publications
5-oxo-15-HETE: total synthesis and bioactivity.
Patel Pranav P Anumolu Jaganmohan R JR Powell William S WS Rokach Joshua J
Bioorganic & medicinal chemistry letters 20110125 6
The first total synthesis of 6(E),8(Z),11(Z),13(E) 5-oxo-15-HETE 4 was accomplished. The synthetic material was evaluated with calcium mobilization assay and compared with 5-oxo-ETE the natural ligand for the OXE receptor. ...[more]
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