Ontology highlight
ABSTRACT:
SUBMITTER: Wang B
PROVIDER: S-EPMC305327 | biostudies-literature | 2003 Nov
REPOSITORIES: biostudies-literature
Reproductive biology and endocrinology : RB&E 20031113
The technology of gene targeting through homologous recombination has been extremely useful for elucidating gene functions in mice. The application of this technology was thought impossible in the large livestock species until the successful creation of the first mammalian clone "Dolly" the sheep. The combination of the technologies for gene targeting of somatic cells with those of animal cloning made it possible to introduce specific genetic mutations into domestic animals. In this review, the ...[more]