Ontology highlight
ABSTRACT:
SUBMITTER: Straub AC
PROVIDER: S-EPMC3056333 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Straub Adam C AC Billaud Marie M Johnstone Scott R SR Best Angela K AK Yemen Sean S Dwyer Scott T ST Looft-Wilson Robin R Lysiak Jeffery J JJ Gaston Ben B Palmer Lisa L Isakson Brant E BE
Arteriosclerosis, thrombosis, and vascular biology 20101111 2
<h4>Objective</h4>To determine whether S-nitrosylation of connexins (Cxs) modulates gap junction communication between endothelium and smooth muscle.<h4>Methods and results</h4>Heterocellular communication is essential for endothelium control of smooth muscle constriction; however, the exact mechanism governing this action remains unknown. Cxs and NO have been implicated in regulating heterocellular communication in the vessel wall. The myoendothelial junction serves as a conduit to facilitate g ...[more]