Ontology highlight
ABSTRACT:
SUBMITTER: Bradbury AR
PROVIDER: S-EPMC3057417 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Nature biotechnology 20110301 3
In vitro display technologies, best exemplified by phage and yeast display, were first described for the selection of antibodies some 20 years ago. Since then, many antibodies have been selected and improved upon using these methods. Although it is not widely recognized, many of the antibodies derived using in vitro display methods have properties that would be extremely difficult, if not impossible, to obtain by immunizing animals. The first antibodies derived using in vitro display methods are ...[more]