Ontology highlight
ABSTRACT:
SUBMITTER: Bhang HE
PROVIDER: S-EPMC3057477 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Bhang Hyo-eun C HE Gabrielson Kathleen L KL Laterra John J Fisher Paul B PB Pomper Martin G MG
Nature medicine 20101212 1
Molecular-genetic imaging is advancing from a valuable preclinical tool to a guide for patient management. The strategy involves pairing an imaging reporter gene with a complementary imaging agent in a system that can be used to measure gene expression or protein interaction or track gene-tagged cells in vivo. Tissue-specific promoters can be used to delineate gene expression in certain tissues, particularly when coupled with an appropriate amplification mechanism. Here we show that the progress ...[more]