Ontology highlight
ABSTRACT:
SUBMITTER: Giglione C
PROVIDER: S-EPMC305796 | biostudies-literature | 2000 Nov
REPOSITORIES: biostudies-literature
Giglione C C Serero A A Pierre M M Boisson B B Meinnel T T
The EMBO journal 20001101 21
The N-terminal protein processing pathway is an essential mechanism found in all organisms. However, it is widely believed that deformylase, a key enzyme involved in this process in bacteria, does not exist in eukaryotes, thus making it a target for antibacterial agents such as actinonin. In an attempt to define this process in higher eukaryotes we have used Arabidopsis thaliana as a model organism. Two deformylase cDNAs, the first identified in any eukaryotic system, and six distinct methionine ...[more]