Enrichment of mRNA-like noncoding RNAs in the divergence of Drosophila males.

ABSTRACT: With the advent of transcriptome data, it has become clear that mRNA-like noncoding RNAs (mlncRNAs) are widespread in eukaryotes. Although their functions are poorly understood, these transcripts may play an important role in development and could thus be involved in determining developmental complexity and phenotypic diversification. However, few studies have assessed their potential roles in the divergence of closely related species. Here, we identify and study patterns of sequence and expression divergence in ten novel candidate mlncRNAs from Drosophila pseudoobscura and its close relative D. persimilis. The candidate mlncRNAs were identified by randomly sequencing a group of 734 cDNA clones from a microarray that showed either no difference in expression (187 clones) or differential ex

SUBMITTER: Jiang ZF 

PROVIDER: S-EPMC3058770 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature