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Persistence of immune responses after a single dose of Novartis meningococcal serogroup A, C, W-135 and Y CRM-197 conjugate vaccine (Menveo®) or Menactra® among healthy adolescents.


ABSTRACT: The persistence of human bactericidal activity (hSBA) responses in adolescents was assessed 22 months after vaccination with one dose of Menveo® (MenACWY-CRM; Novartis) or Menactra® (MCV4) (sanofi pasteur). The proportion of subjects with hSBA titers ?8 was significantly higher among recipients of MenACWY-CRM than MCV4 for serogroups A, W-135 and Y.

SUBMITTER: Gill CJ 

PROVIDER: S-EPMC3060384 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature

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Persistence of immune responses after a single dose of Novartis meningococcal serogroup A, C, W-135 and Y CRM-197 conjugate vaccine (Menveo®) or Menactra® among healthy adolescents.

Gill Christopher J CJ   Baxter Roger R   Anemona Alessandra A   Ciavarro Giuseppe G   Dull Peter P  

Human vaccines 20101101 11


The persistence of human bactericidal activity (hSBA) responses in adolescents was assessed 22 months after vaccination with one dose of Menveo® (MenACWY-CRM; Novartis) or Menactra® (MCV4) (sanofi pasteur). The proportion of subjects with hSBA titers ≥8 was significantly higher among recipients of MenACWY-CRM than MCV4 for serogroups A, W-135 and Y. ...[more]

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