Ontology highlight
ABSTRACT:
SUBMITTER: Hulme SE
PROVIDER: S-EPMC3060707 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Hulme S Elizabeth SE Shevkoplyas Sergey S SS McGuigan Alison P AP Apfeld Javier J Fontana Walter W Whitesides George M GM
Lab on a chip 20091218 5
This article describes the fabrication of a microfluidic device for the liquid culture of many individual nematode worms (Caenorhabditis elegans) in separate chambers. Each chamber houses a single worm from the fourth larval stage until death, and enables examination of a population of individual worms for their entire adult lifespans. Adjacent to the chambers, the device includes microfluidic worm clamps, which enable periodic, temporary immobilization of each worm. The device made it possible ...[more]