Ontology highlight
ABSTRACT:
SUBMITTER: Cai T
PROVIDER: S-EPMC3062150 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Cai Tianxi T Tian Lu L Wong Peggy H PH Wei L J LJ
Biostatistics (Oxford, England) 20100928 2
Suppose that under the conventional randomized clinical trial setting, a new therapy is compared with a standard treatment. In this article, we propose a systematic, 2-stage estimation procedure for the subject-level treatment differences for future patient's disease management and treatment selections. To construct this procedure, we first utilize a parametric or semiparametric method to estimate individual-level treatment differences, and use these estimates to create an index scoring system f ...[more]