Ontology highlight
ABSTRACT:
SUBMITTER: Yang S
PROVIDER: S-EPMC3062151 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Yang Song S Prentice Ross L RL
Biostatistics (Oxford, England) 20100921 2
The hazard ratio provides a natural target for assessing a treatment effect with survival data, with the Cox proportional hazards model providing a widely used special case. In general, the hazard ratio is a function of time and provides a visual display of the temporal pattern of the treatment effect. A variety of nonproportional hazards models have been proposed in the literature. However, available methods for flexibly estimating a possibly time-dependent hazard ratio are limited. Here, we in ...[more]