Unknown

Dataset Information

0

Hepatitis E virus infections in swine and swine handlers in Vellore, Southern India.


ABSTRACT: Hepatitis E virus (HEV) in industrialized countries is zoonotically transmitted, and swine act as a major reservoir of HEV. Serum samples from 102 swine and plasma from 34 swine handlers in Vellore, India were tested by using a reverse transcription-polymerase chain reaction to detect and genotype HEV. We measured levels of IgG against HEV in swine handlers and in age and geographically matched controls from rural and urban populations in Vellore. HEV was amplified from two pigs and both viruses belonged to genotype 4. No HEV RNA was amplified from any swine handler, but 94.1% of swine handlers were positive for antibodies against HEV, a seroprevalence rate significantly higher than in rural and urban controls. The HEV genotype circulating in swine in India is different from that of humans, but the higher antibody levels in swine handlers support the possibility that zoonotic infections may occur.

SUBMITTER: Vivek R 

PROVIDER: S-EPMC3062464 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature

altmetric image

Publications

Hepatitis E virus infections in swine and swine handlers in Vellore, Southern India.

Vivek Rosario R   Kang Gagandeep G  

The American journal of tropical medicine and hygiene 20110401 4


Hepatitis E virus (HEV) in industrialized countries is zoonotically transmitted, and swine act as a major reservoir of HEV. Serum samples from 102 swine and plasma from 34 swine handlers in Vellore, India were tested by using a reverse transcription-polymerase chain reaction to detect and genotype HEV. We measured levels of IgG against HEV in swine handlers and in age and geographically matched controls from rural and urban populations in Vellore. HEV was amplified from two pigs and both viruses  ...[more]

Similar Datasets

| S-EPMC5454524 | biostudies-literature
| S-EPMC3028948 | biostudies-literature
| S-EPMC2473265 | biostudies-literature
| S-EPMC2876739 | biostudies-literature
| S-EPMC3550797 | biostudies-literature
| S-EPMC3919735 | biostudies-literature
| S-EPMC6552319 | biostudies-literature
| S-EPMC4736149 | biostudies-other
| S-EPMC4136299 | biostudies-literature
| S-EPMC6533384 | biostudies-literature