Ontology highlight
ABSTRACT:
SUBMITTER: Trenerry MK
PROVIDER: S-EPMC3063215 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Trenerry Marissa K MK Della Gatta Paul A PA Cameron-Smith David D
BMC physiology 20110309
<h4>Background</h4>A population of satellite cells exists in skeletal muscle. These cells are thought to be primarily responsible for postnatal muscle growth and injury-induced muscle regeneration. The Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling cascade has a crucial role in regulating myogenesis. In rodent skeletal muscle, STAT3 is essential for satellite cell migration and myogenic differentiation, regulating the expression of myogenic factors. The aim ...[more]