Ontology highlight
ABSTRACT:
SUBMITTER: Gokarn YR
PROVIDER: S-EPMC3064836 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Gokarn Yatin R YR Fesinmeyer R Matthew RM Saluja Atul A Razinkov Vladimir V Chase Susan F SF Laue Thomas M TM Brems David N DN
Protein science : a publication of the Protein Society 20110301 3
Specific-ion effects are ubiquitous in nature; however, their underlying mechanisms remain elusive. Although Hofmeister-ion effects on proteins are observed at higher (>0.3 M) salt concentrations, in dilute (<0.1 M) salt solutions nonspecific electrostatic screening is considered to be dominant. Here, using effective charge (Q*) measurements of hen-egg white lysozyme (HEWL) as a direct and differential measure of ion-association, we experimentally show that anions selectively and preferentially ...[more]