Ontology highlight
ABSTRACT:
SUBMITTER: Turner S
PROVIDER: S-EPMC3066182 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Turner Stephen S Armstrong Loren L LL Bradford Yuki Y Carlson Christopher S CS Crawford Dana C DC Crenshaw Andrew T AT de Andrade Mariza M Doheny Kimberly F KF Haines Jonathan L JL Hayes Geoffrey G Jarvik Gail G Jiang Lan L Kullo Iftikhar J IJ Li Rongling R Ling Hua H Manolio Teri A TA Matsumoto Martha M McCarty Catherine A CA McDavid Andrew N AN Mirel Daniel B DB Paschall Justin E JE Pugh Elizabeth W EW Rasmussen Luke V LV Wilke Russell A RA Zuvich Rebecca L RL Ritchie Marylyn D MD
Current protocols in human genetics 20110101
Genome-wide association studies (GWAS) are being conducted at an unprecedented rate in population-based cohorts and have increased our understanding of the pathophysiology of complex disease. Regardless of context, the practical utility of this information will ultimately depend upon the quality of the original data. Quality control (QC) procedures for GWAS are computationally intensive, operationally challenging, and constantly evolving. Here we enumerate some of the challenges in QC of GWAS da ...[more]