Ontology highlight
ABSTRACT:
SUBMITTER: Tamiya N
PROVIDER: S-EPMC3066545 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Tamiya Nobuo N Yagi Tatsuhiko T
Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110101 3
Erabutoxins a and b are neurotoxins isolated from venom of a sea snake Laticauda semifasciata (erabu-umihebi). Amino acid sequences of the toxins indicated that the toxins are members of a superfamily consisting of short and long neurotoxins and cytotoxins found in sea snakes and terrestrial snakes. The short neurotoxins to which erabutoxins belong act by blocking the nicotinic acetylcholine receptor on the post synaptic membrane in a manner similar to that of curare. X-ray crystallography and N ...[more]