Ontology highlight
ABSTRACT:
SUBMITTER: Park SR
PROVIDER: S-EPMC3068488 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Park S R SR Kong S-Y SY Nam B-H BH Choi I J IJ Kim C G CG Lee J Y JY Cho S J SJ Kim Y W YW Ryu K W KW Lee J H JH Rhee J J Park Y-I YI Kim N K NK
British journal of cancer 20110301 7
<h4>Background</h4>We evaluated the association between polymorphisms of cytochrome P450 2A6 (CYP2A6)/excision repair cross-complementation group 1 (ERCC1)/X-ray repair cross-complementing group 1(XRCC1) and treatment outcomes of metastatic gastric cancer (MGC) patients treated with S-1/cisplatin.<h4>Methods</h4>Among MGC patients (n=108), who received S-1 (40 mg m(-2) b.i.d., days 1-14) and cisplatin (60 mg m(-2), day 1) every 3 weeks, we analysed the wild-type allele (W) and variants (V) of CY ...[more]