An infant-associated bacterial commensal utilizes breast milk sialyloligosaccharides.
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ABSTRACT:
SUBMITTER: Sela DA
PROVIDER: S-EPMC3069393 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
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An infant-associated bacterial commensal utilizes breast milk sialyloligosaccharides.
Sela David A DA Li Yanhong Y Lerno Larry L Wu Shuai S Marcobal Angela M AM German J Bruce JB Chen Xi X Lebrilla Carlito B CB Mills David A DA
The Journal of biological chemistry 20110202 14
Lactating mothers secrete milk sialyloligosaccharides (MSOs) that function as anti-adhesives once provided to the neonate. Particular infant-associated commensals, such as Bifidobacterium longum subsp. infantis, consume neutral milk oligosaccharides, although their ability to utilize acidic oligosaccharides has not been assessed. Temporal glycoprofiling of acidic HMO consumed during fermentation demonstrated a single composition, with several isomers, corresponding to sialylated lacto-N-tetraose ...[more]
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