Ontology highlight
ABSTRACT:
SUBMITTER: Wu IC
PROVIDER: S-EPMC3071087 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Wu I-Chen IC Zhao Yang Y Zhai Rihong R Liu Geoffrey G Ter-Minassian Monica M Asomaning Kofi K Su Li L Liu Chen-Yu CY Chen Feng F Kulke Matthew H MH Heist Rebecca S RS Christiani David C DC
Neoplasia (New York, N.Y.) 20110401 4
There is an increasing incidence of esophageal adenocarcinoma (EA) among younger people in the western populations. However, the association between genetic polymorphisms and the age of EA onset is unclear. In this study, 1330 functional/tagging single-nucleotide polymorphisms (SNPs) from 354 cancer-related genes were genotyped in 335 white EA patients. Twenty important SNPs that have the highest importance scores and lowest classification error rate were identified by the random forest algorith ...[more]