Next generation sequence assembly with AMOS.
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ABSTRACT:
SUBMITTER: Treangen TJ
PROVIDER: S-EPMC3072823 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Publications
Next generation sequence assembly with AMOS.
Treangen Todd J TJ Sommer Dan D DD Angly Florent E FE Koren Sergey S Pop Mihai M
Current protocols in bioinformatics 20110301
A Modular Open-Source Assembler (AMOS) was designed to offer a modular approach to genome assembly. AMOS includes a wide range of tools for assembly, including the lightweight de novo assemblers Minimus and Minimo, and Bambus 2, a robust scaffolder able to handle metagenomic and polymorphic data. This protocol describes how to configure and use AMOS for the assembly of Next Generation sequence data. Additionally, we provide three tutorial examples that include bacterial, viral, and metagenomic d ...[more]
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