Phenotypic and genotypic variations within a single bacteriophage species.
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ABSTRACT:
SUBMITTER: Ceyssens PJ
PROVIDER: S-EPMC3072928 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Publications
Phenotypic and genotypic variations within a single bacteriophage species.
Ceyssens Pieter-Jan PJ Glonti Thea T Kropinski Ndrew M NM Lavigne Rob R Chanishvili Nina N Kulakov Leonid L Lashkhi Nino N Tediashvili Marina M Merabishvili Maya M
Virology journal 20110323
<h4>Background</h4>Although horizontal gene transfer plays a pivotal role in bacteriophage evolution, many lytic phage genomes are clearly shaped by vertical evolution. We investigated the influence of minor genomic deletions and insertions on various phage-related phenotypic and serological properties.<h4>Findings</h4>We collected ten different isolates of Pseudomonas aeruginosa bacteriophage ϕKMV. All sequenced genomes (42-43 kb, long direct terminal repeats) are nearly identical, which intuit ...[more]
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