Ontology highlight
ABSTRACT:
SUBMITTER: Imoukhuede PI
PROVIDER: S-EPMC3073416 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Imoukhuede P I PI Popel Aleksander S AS
Experimental cell research 20101223 7
The vascular endothelial growth factor receptors (VEGFR) play a significant role in angiogenesis, the formation of new blood vessels from existing vasculature. Systems biology offers promising approaches to better understand angiogenesis by computational modeling the key molecular interactions in this process. Such modeling requires quantitative knowledge of cell surface density of pro-angiogenic receptors versus anti-angiogenic receptors, their regulation, and their cell-to-cell variability. Us ...[more]