Ontology highlight
ABSTRACT:
SUBMITTER: Stephensen CB
PROVIDER: S-EPMC3073473 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
Stephensen Charles B CB Armstrong Patrice P Newman John W JW Pedersen Theresa L TL Legault Jillian J Schuster Gertrud U GU Kelley Darshan D Vikman Susanna S Hartiala Jaana J Nassir Rami R Seldin Michael F MF Allayee Hooman H
Journal of lipid research 20110204 5
The objective of this study was to determine whether 5-lipoxygenase (ALOX5) gene variants associated with cardiovascular disease affect eicosanoid production by monocytes. The study was a randomized, double-masked, parallel intervention trial with fish oil (5.0 g of fish oil daily, containing 2.0 g of eicosapentaenoic acid [EPA] and 1.0 g of docosahexaenoic acid [DHA]) or placebo oil (5.0 g of corn/soy mixture). A total of 116 subjects (68% female, 20-59 years old) of African American ancestry e ...[more]