Ontology highlight
ABSTRACT:
SUBMITTER: Dutta R
PROVIDER: S-EPMC3073544 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Annals of neurology 20110301 3
<h4>Objective</h4>Multiple Sclerosis (MS) is an inflammatory demyelinating disease of the human central nervous system. Although the clinical impact of gray matter pathology in MS brains is unknown, 30 to 40% of MS patients demonstrate memory impairment. The molecular basis of this memory dysfunction has not yet been investigated in MS patients.<h4>Methods</h4>To investigate possible mechanisms of memory impairment in MS patients, we compared morphological and molecular changes in myelinated and ...[more]