Ontology highlight
ABSTRACT:
SUBMITTER: Rantala JK
PROVIDER: S-EPMC3073923 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Rantala Juha K JK Mäkelä Rami R Aaltola Anna-Riina AR Laasola Petra P Mpindi John-Patrick JP Nees Matthias M Saviranta Petri P Kallioniemi Olli O
BMC genomics 20110328
<h4>Background</h4>High-throughput RNAi screening is widely applied in biological research, but remains expensive, infrastructure-intensive and conversion of many assays to HTS applications in microplate format is not feasible.<h4>Results</h4>Here, we describe the optimization of a miniaturized cell spot microarray (CSMA) method, which facilitates utilization of the transfection microarray technique for disparate RNAi analyses. To promote rapid adaptation of the method, the concept has been test ...[more]