Ontology highlight
ABSTRACT:
SUBMITTER: Grossoehme N
PROVIDER: S-EPMC3075698 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Grossoehme Nicholas N Kehl-Fie Thomas E TE Ma Zhen Z Adams Keith W KW Cowart Darin M DM Scott Robert A RA Skaar Eric P EP Giedroc David P DP
The Journal of biological chemistry 20110221 15
All strains of Staphylococcus aureus encode a putative copper-sensitive operon repressor (CsoR) and one other CsoR-like protein of unknown function. We show here that NWMN_1991 encodes a bona fide Cu(I)-inducible CsoR of a genetically unlinked copA-copZ copper resistance operon in S. aureus strain Newman. In contrast, an unannotated open reading frame found between NWMN_0027 and NWMN_0026 (denoted NWMN_0026.5) encodes a CsoR-like regulator that represses expression of adjacent genes by binding s ...[more]