Ontology highlight
ABSTRACT:
SUBMITTER: Wang LS
PROVIDER: S-EPMC3076314 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Wang Li-Shu LS Arnold Mark M Huang Yi-Wen YW Sardo Christine C Seguin Claire C Martin Edward E Huang Tim H-M TH Riedl Ken K Schwartz Steven S Frankel Wendy W Pearl Dennis D Xu Yiqing Y Winston John J Yang Guang-Yu GY Stoner Gary G
Clinical cancer research : an official journal of the American Association for Cancer Research 20101201 3
<h4>Purpose</h4>This study evaluated the effects of black raspberries (BRBs) on biomarkers of tumor development in the human colon and rectum including methylation of relevant tumor suppressor genes, cell proliferation, apoptosis, angiogenesis, and expression of Wnt pathway genes.<h4>Experimental design</h4>Biopsies of adjacent normal tissues and colorectal adenocarcinomas were taken from 20 patients before and after oral consumption of BRB powder (60 g/d) for 1-9 weeks. Methylation status of pr ...[more]