Effect of statin therapy on disease progression in pediatric ADPKD: design and baseline characteristics of participants.
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SUBMITTER: Cadnapaphornchai MA
PROVIDER: S-EPMC3077046 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
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Effect of statin therapy on disease progression in pediatric ADPKD: design and baseline characteristics of participants.
Cadnapaphornchai Melissa A MA George Diana M DM Masoumi Amirali A McFann Kim K Strain John D JD Schrier Robert W RW
Contemporary clinical trials 20110123 3
Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic kidney condition and is associated with important renal and cardiovascular manifestations in childhood. Renal cystic disease can be documented in some cases as early as in utero. Early intervention is critical if the long-term complications of this condition, including end-stage renal disease, are to be ameliorated. Here we describe our ongoing randomized double-blind placebo-controlled phase III clinical trial to as ...[more]
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