Ontology highlight
ABSTRACT:
SUBMITTER: Wang Y
PROVIDER: S-EPMC3078443 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Wang Yu Y Hancock Aneeka M AM Bradner Joshua J Chung Kathryn A KA Quinn Joseph F JF Peskind Elaine R ER Galasko Douglas D Jankovic Joseph J Zabetian Cyrus P CP Kim Hojoong M HM Leverenz James B JB Montine Thomas J TJ Ginghina Carmen C Edwards Karen L KL Snapinn Katherine W KW Goldstein David S DS Shi Min M Zhang Jing J
The American journal of pathology 20110401 4
Complement activation, a key component of neuroinflammation, has been reported in both Parkinson's disease (PD) and Alzheimer's disease (AD). However, it is unclear whether complement activation and neuroinflammation in general are distinctly different from each another in major neurodegenerative disorders. In the present study, cerebrospinal fluid complement 3 (C3) and factor H (FH) were measured and evaluated together with amyloid-β(42) (Aβ(42)), which in recent investigations was decreased in ...[more]