Ontology highlight
ABSTRACT:
SUBMITTER: Garcia-Torres I
PROVIDER: S-EPMC3078909 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
García-Torres Itzhel I Cabrera Nallely N Torres-Larios Alfredo A Rodríguez-Bolaños Mónica M Díaz-Mazariegos Selma S Gómez-Puyou Armando A Perez-Montfort Ruy R
PloS one 20110418 4
For a better comprehension of the structure-function relationship in proteins it is necessary to identify the amino acids that are relevant for measurable protein functions. Because of the numerous contacts that amino acids establish within proteins and the cooperative nature of their interactions, it is difficult to achieve this goal. Thus, the study of protein-ligand interactions is usually focused on local environmental structural differences. Here, using a pair of triosephosphate isomerase e ...[more]